Adding/Updated MOCR protocols

To add protocols used in recent papers by the Mimosa-NSMRL-MIT team of MOCR researchers:

  1. If you have a new HearID+MOCR system, or if you have not added or edited the factory default protocols that ship with HearID, ask Mimosa for the updated 2023 protocols (mocr_parsets.mat and CAS8kHzFilter.mat).
  2. If you have an existing HearID+MOCR system AND have added to or edited the factory defaults, ask Mimosa to update and append your MOCR parsets file with the new protocols. Otherwise copying over the new factory default version will wipe your protocols.
    1. Find your current mocr_parsets.mat file in your HearID program folder.
    2. Zip and transfer it via your preferred cloud file transfer method (WeTransfer, Dropbox) to support@mimosaacoustics.com. The file is small, but most email programs will intercept *.mat files so do not directly email the file as it may end up in our spam folder.
  3. When you receive the updated mocr_parsets.mat file and the new CAS8kHzFilter.mat file, make sure HearID is not running. Make a backup of your current mocr_parsets.mat file then copy the new files into your HearID program folder. 
  4. Run HearID and from the menu open MOCR | Parameters. You should see the new protocols at the end of the protocol list. 
    1. You can reorder them and choose a default as desired. You may also edit them, but if you do, we recommend saving them with a new name rather than overwriting them. 
    2. Be aware that if you edit the related TEOAE or SFOAE protocol, multiple MOCR protocols may link to them. By clicking on the MOCR protocol name, the OAE protocol list will update to show you which is connected.

Protocol documentation

MOCR protocols

Four new MOCR protocols from Lapsley Miller, Reed, Marshall, Perez, and Villabona (2023) are now available in our factory default package for HearID. See Table 1 for the key parameters in the underlying TEOAE protocols.

As a reminder, a MOCR protocol consists of the MOCR parameters controlling the presentation and timing of “Quiet” and “Noise” OAE trials, and the OAE parameters (saved as separate OAE protocols). Multiple MOCR protocols can point to the same OAE protocol. Open MOCR Parameters to see how they relate, and refer to the MOCR user manual for more general information about protocols and parameters.

The “E1” protocols are identical to the HearID protocols used in Experiment 1 from Lapsley Miller et al. (2023).

The “E2” protocols are similar to the OtoStat protocols used in Experiment 2 from Lapsley Miller et al. (2023) and give comparable results, but have the important difference that they do not use in situ FPL calibration. You can use the paper's 0.2-8 kHz bandpass filter or the default 10 kHz low-pass contralateral noise filter. Bandpass noise from 0.2-8 kHz was chosen to match the bandwidth available for FPL calibration on the OtoStat, but is unlikely to give marked differences in the measured MOCR from the 10 kHz default.

E1_LinearClick50_EH23

This MOCR protocol is paired with TEOAE protocol E1_Linear_Click_EH23.

E1_NonLinearChirp50_EH23

This MOCR protocol is paired with TEOAE protocol E1_NonLinear_Chirp_EH23.

E2_LinearClick50_15_EH23

This MOCR protocol is paired with TEOAE protocol E2_LinearClick50_15_EH23. It uses a 15 dB SNR stopping rule.

E2_LinearClick50_20_EH23

This MOCR protocol is paired with TEOAE protocol E2_LinearClick50_20_EH23. It uses a 20 dB SNR stopping rule.

Using a different contralateral noise filter

If you wish to use the 0.2-8 kHz broadband noise filter, ensure the CAS8kHzFilter.mat file is copied into your HearID program folder, then manually turn it on by editing mocr_hardware.cfg in a plain-text editor to point the filter name to the correct file:

parameter series.filtFileName = 'CAS8kHzFilter.mat' ;

To use the 10 kHz default filter, leave this field blank

parameter series.filtFileName = '';

Be sure to use plain, not curly, quotes.

This is a global change and will modify the broadband noise stimulus for all MOCR protocols. Any other filter may be used by designing it in Matlab (see the instructions in the Parameters section of the MOCR user manual).

In our experiments, we switched between filters by writing simple scripts to load different versions of the mocr_hardware.cfg file, restarting HearID in between so that the changed configuration was activated.

References

Lapsley Miller, J. A., Reed, C. M., Marshall, L., Perez, Z. D., & Villabona, T. (2023). A Clinically Viable Medial Olivocochlear Reflex Assay Using Transient-Evoked Otoacoustic Emissions. Ear and Hearing. Publish-ahead-of-print

Prepared by

Judi Lapsley Miller, Ph.D.

Senior Scientist, Mimosa Acoustics, Inc.

judi@mimosaacoustics.com

1 Sep 2023

General Documentation 0000320


Table 1. Key TEOAE parameters from Lapsley Miller et al. (2023), including stimulus level, mode, stimulus bandwidth and duration, response window (onset and duration), inter-stimulus interval (ISI), maximum averages and rejections (if early stopping rules did not apply), early stopping signal-to-noise ratio (SNR), contralateral noise bandwidth. In this paper, the Experiment 2 protocol was run on OtoStat with FPL calibration, but this is the HearID equivalent (with spectrum-compensated SPL calibration).

Experiment

Protocol Name

Stimulus type

Stimulus level (dB SPL)

Mode

Stimulus bandwidth (kHz)

Stimulus duration (ms)

Response bandwidth (kHz)

 

 

Analyzed band (kHz)

Response window delay/ramp/duration (ms)

 

 

 

Maximum 

Averages/Rejections

Early stopping rule SNR (dB)

Early stopping rule noise level (dB SPL)

Contralateral bandwidth (kHz)

1

E1_NonLinearChirp50_EH23

Chirp

50

Non-linear

1-5

10.5

1-5

 

0.5-2.5

2/2.5/14

615/500

6

-6

~10

1

E1_LinearClick50_EH23

Click

50

Linear

0.5-2.5

4

1-2.5
 

0.5-2.5

5/2.5/13

2000/2000

20

-6

~10

2

E2_LinearClick50_15_EH23

E2_LinearClick50_20_EH23

Click

50

Linear

1-3

4

1-3

1-3

5/2.5/13

1000/400

15 20

-10

~0.2-8


DISCLAIMER: Before testing in real ears, the onus is on you to ensure the contralateral sound levels are safe and accurate. It is not possible for HearID to determine that you have set safe and accurate levels. Mimosa Acoustics expects that any use of the MOCR CAS system on human or animal ears has approval from your institutional review board. This add-on is for research use only.